![]() There are several mechanisms by which a positive effect on the lower limb tissue perfusion is conferred by the use of IPC. Attempts to support the inflow of arterial blood to ischemic limb regions by means of pneumatic pumps and sleeves have a long tradition. Despite of IPC technology having been available in its present form for many years uncertainty remains about its mechanism to improve arterial inflow and clinical effectiveness in a population who are in urgent need of effective treatment options. There is no objective data, except hypotheses from the academic centers, documenting the mechanism of increasing the arterial flow and increasing the knowledge of the beneficial effects. The only treatment here is increasing blood peripheral tissue flow with the help of external support by intermittent pneumatic compression devices (IPC). There is a large group of patients with ischemia of the lower leg and foot without effect of the pharmacological treatment who are not eligible for surgical reconstruction of the arteries due multi-segmental arterial obstruction and general contraindications for major surgery. ![]() Pharmacological treatment, especially with statins, limited the indications for surgical treatment, created a challenge for more effective conservative treatment. Ischemia of lower limbs due to atherosclerosis of arteries causing intermittent claudication, and in cases of more advanced state necrotic changes of peripheral tissues, concerns in the age group above 60 years between 1% and 7% of the population.
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